PROBABLE ANALGESIC EFFECT OF SYNTHETIC TETRAPEPTIDE
نویسندگان
چکیده
منابع مشابه
Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial.
CONTEXT 1',1'dimethylheptyl-Delta8-tetrahydrocannabinol-11-oic acid (CT-3), a potent analog of THC-11-oic acid, produces marked antiallodynic and analgesic effects in animals without evoking the typical effects described in models of cannabinoids. Therefore, CT-3 may be an effective analgesic for poorly controlled resistant neuropathic pain. OBJECTIVE To examine the analgesic efficacy and saf...
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Single crystal X-ray diffraction studies on the water soluble, synthetic tetrapeptide Tyr(1)-Aib(2)-Tyr(3)-Val(4) with a non-coded amino acid residue (Aib: [small alpha]-amino isobutyric acid) reveal that the peptide adopts an "S"-shaped molecular structure which self-assembles to form a supramolecular triple helix using various non-covalent interactions including water mediated hydrogen bonds ...
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The effect of halothane on experimental ischaemic muscle pain has been studied in 18 human volunteers. The submaxiTniim effort tourniquet test was used in this investigation because it has been shown by previous workers to be a sensitive experimental test of analgesia. Two concentrations of halothane (0.25 and 0.35%) were compared with nitrous oxide (30%) in a controlled experiment. It was foun...
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Ten new synthetic thiazolidine-4-ones derivatives (5 chlorothiazolidine-4-ones, 3 methoxythiazolidine-4-ones and 2 hydoxythiazolidine-4-ones) having different substituents at R1, R2 and R3 were evaluated for their analgesic activity using different animal models and their structure activity relationship was also elucidated. Chlorothiazolidine-4-ones and methoxythiazolidine-4-ones exhibited anal...
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ژورنال
عنوان ژورنال: Medical academic journal
سال: 2019
ISSN: 1608-4101
DOI: 10.17816/maj191s1172-174